As someone seeking information about Dexedrine vs Adderall to determine which is right for you, you’ll want to understand the differences between these medications in detail. Dexedrine and Adderall are both stimulants used to treat attention deficit hyperactivity disorder (ADHD), but they have distinct differences in their formulations, dosages, side effects, addiction potential, withdrawal timelines, and treatment options.
What Is Dexedrine (Dextroamphetamine)?
Dextroamphetamine, widely known as d-amphetamine, is the most potent amphetamine available for medical use. Available under various brand names, including Dexedrine, ProCentra, and Zenzedi, dextroamphetamine is a potent central nervous system stimulant. It specifically targets neurotransmitters in the brain, notably dopamine and norepinephrine, enhancing focus, and attention, and controlling impulsivity. Its direct and potent action makes it a powerful option for treating ADHD and narcolepsy. Being a single-component drug, its effects primarily stem from its singular amphetamine isomer, known for its strong stimulant properties.
Dextroamphetamine, commonly known by the street name “Dexie” or “Dexies,” carries a notable potential for abuse and addiction. This risk is considerably high, particularly due to its potent stimulant effects. Misuse, such as taking higher doses than prescribed or for recreational purposes, can lead to severe dependency. This addiction can have life-altering consequences, leading to significant health problems, behavioral changes, and serious psychological disorders.
What does Dexedrine Look Like?
Dexedrine comes in different forms, such as immediate-release tablets and Dexedrine Spansule, an extended-release capsule.
- Dexedrine 5mg pill is orange and three-sided, imprinted with “SKF E19.”
- Dexedrine Spansule 5 mg is a brown capsule, imprinted with “3512” and “5 mg.”
- Dexedrine Spansule 10 mg is a brown capsule, imprinted with “3513” and “10 mg.”
- Dexedrine Spansule 15 mg is a brown and clear capsule, imprinted with “3514” and “15.”Dextroamphetamine Side Effects
Is dextroamphetamine stronger than Adderall?
Dextroamphetamine and Adderall are both stimulants used to treat ADHD. Dextroamphetamine contains dextroamphetamine sulfate, while Adderall contains dextroamphetamine sulfate and amphetamine sulfate. Dextroamphetamine is considered slightly stronger than Adderall.
Dextroamphetamine comes in doses of 5 mg, 10 mg, and 15 mg. Adderall comes in doses of 5 mg, 10 mg, 20 mg, and 30 mg. So while Adderall may seem stronger based on dosage, the dextroamphetamine in the pills provides slightly stronger effects.
What is the difference between Dexedrine and Adderall?
Compared to Adderall, Dexedrine only contains dextroamphetamine, while Adderall contains a mixture of dextroamphetamine and levoamphetamine. Dexedrine may have fewer side effects for some people. However, Adderall XR does provide longer symptom control with a single dose. Dexedrine also has a higher addiction potential and risk of withdrawal symptoms if stopped abruptly compared to Adderall XR.
Differences in Addictive Potential
Both Dexedrine and Adderall have the potential for abuse and addiction, though studies have found that Dexedrine may be slightly less addictive. This is likely due to Dexedrine containing only dextroamphetamine, while Adderall contains both amphetamine and dextroamphetamine. The amphetamine component in Adderall may contribute to a higher abuse and addiction potential.
Still, both medications require close monitoring and have risks of abuse, misuse, and addiction if not taken as prescribed. Symptoms of stimulant addiction or abuse include:
- Taking higher doses than prescribed
- Taking the medication more frequently
- Experiencing withdrawal symptoms when the drug wears off
- Taking the medication for non-medical reasons, like to get high
- Experiencing negative side effects that impact functioning
If you have a history of substance use disorder or are at risk of addiction, a non-stimulant medication may be a safer option to discuss with your doctor. With proper use, monitoring, and follow-up care, Dexedrine and Adderall can be effective ADHD treatments when used as directed under a physician’s supervision.
Key Differences Between Dexedrine and Adderall
Potency
Dexedrine only contains dextroamphetamine, while Adderall contains both dextroamphetamine and levoamphetamine. Dextroamphetamine is considered the more potent form, so Dexedrine may have stronger effects, especially milligram for milligram. Adderall XR, the extended-release form of Adderall, contains more dextroamphetamine, so it tends to be stronger than regular Adderall.
Dosage Comparison: Dexedrine vs. Adderall
- Dexedrine:
- Immediate-Release Capsules: Available in 5 mg, 10 mg, and 15 mg.
- Extended-Release (Spansule) Capsules: Also in 5 mg, 10 mg, and 15 mg doses.
- Adderall:
- Immediate-Release Tablets: Doses include 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg, 20 mg, and 30 mg.
- Extended-Release (XR) Capsules: Come in 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, and 30 mg.
For ADHD treatment:
- Dexedrine Starting Dose: 5 mg once or twice daily for children, and 10 mg once or twice daily for adults, with increases in 5 mg steps. Maximum daily dose: 60 mg for adults, 40 mg for ages 6-17.
- Adderall Starting Dose: Typically 5-10 mg once or twice daily for children and adults, also increased in 5 mg increments. Maximum daily dose: 40 mg for ages 13-17, 60 mg for adults.
Side Effects: Dexedrine, Dextroamphetamine vs Adderall
Common side effects of Dexedrine and Adderall include:
- Loss of appetite and weight loss
- Sleep difficulties
- Nervousness and restlessness
- Dry mouth
- Nausea and stomach pain
Adderall may produce additional side effects like headaches, dizziness, and increased heart rate due to its extra amphetamine components. High doses or long-term use of Dextroamphetamine and Adderall can also lead to more serious side effects such as psychosis, heart problems, and growth suppression in children.
Individuals using Dexedrine might experience less restlessness, agitation, and mood changes compared to those on Adderall. Furthermore, the rebound or crash effect experienced as the medication wears off could be less severe with Dexedrine, due to its different pharmacological profile.
While dextroamphetamine and Adderall can be effective for ADHD and narcolepsy, their similar stimulating effects also come with risks around addiction, withdrawal, and side effects that require close monitoring. Comparing the specific differences in their formulations and impacts can help determine which may be safer or more suitable for you. But in either case, these potent stimulants should only be used under medical supervision and according to instructions.
Duration: Dexedrine vs Adderall
How Long Do Dexedrine and Adderall Take to Work?
The effects of these stimulants can take effect within 30 to 60 minutes of taking the medication.
Dexedrine: Immediate vs. Extended Release
- Dexedrine (Immediate Release): The effects typically begin within 30 to 60 minutes and last about 4 to 6 hours, with peak blood concentration within 1 to 3 hours.
- Dexedrine Spansule (Extended Release): Offers a longer duration of action, lasting between 8 to 12 hours, suitable for all-day symptom management.
Adderall: Immediate vs. Extended Release
- Adderall (Immediate Release): Similar to Dexedrine, the effects start within 30 to 60 minutes and last for 4 to 6 hours, with peak concentration in the blood occurring 1 to 3 hours after taking the dose.
- Adderall XR (Extended Release): Provides an extended duration of about 8 to 12 hours, beneficial for consistent day-long coverage.
Both the immediate-release forms of Dexedrine and Adderall have similar effective durations, as do their extended-release counterparts. This makes them both viable options for ADHD treatment, allowing for flexible dosing schedules that align with individual needs.
How Long Does Dexedrine and Adderall Last?
Dexedrine typically lasts 6 to 8 hours, while Adderall XR can last 10 to 12 hours due to its extended-release mechanism. The immediate-release Adderall usually lasts 4 to 6 hours. For those wanting longer coverage or once-daily dosing, Adderall XR may be preferable.
Addiction and Withdrawal
Dexedrine and Adderall can be addictive, especially if misused at high doses or injected/snorted, but Dexedrine may have a slightly lower addiction potential due to containing only dextroamphetamine.
Stopping dextroamphetamine or Adderall abruptly can lead to withdrawal symptoms. These may include:
- Fatigue and sleep problems
- Irritability and mood changes
- Difficulty concentrating
- Increased appetite
Withdrawal from Adderall may be more severe compared to dextroamphetamine due to its additional amphetamine salts. The withdrawal timeline can last 1-2 weeks for both drugs. A gradual taper under medical guidance is recommended to minimize withdrawal effects.
Addiction Potential: Is Dexedrine or Adderall More Addictive?
When it comes to addiction potential, Adderall and Dexedrine are quite similar. Both contain amphetamine, a stimulant that works by increasing dopamine and norepinephrine levels in the brain. This can lead to dependence and addiction over time or with high doses. However, some factors may make one slightly more addictive than the other.
Adderall contains a mixture of amphetamine salts: dextroamphetamine and levoamphetamine. Dextroamphetamine is considered the more potent isomer, meaning it has a stronger effect on the central nervous system. Adderall’s mixture of amphetamine salts may produce a stronger high or euphoria due to the presence of dextroamphetamine. This could increase the reward effect in the brain and the desire to reuse the drug, contributing to addiction.
Dexedrine, on the other hand, contains dextroamphetamine alone. While still highly addictive, dextroamphetamine by itself may have slightly less addiction potential compared to the mixture in Adderall. The specific formulation and ratio of amphetamine isomers seem to play some role in the addictiveness of these stimulants.
Both Adderall and Dexedrine are classified as Schedule II controlled substances by the DEA due to their high potential for abuse and addiction. When misused or taken in high doses, these drugs can lead to dangerous side effects like psychosis, heart problems, and even sudden death. The risk of overdose and addiction is higher if you crush or snort the pills, or inject the contents.
Dexedrine vs Adderall Withdrawal Timelines: What to Expect When Stopping
When stopping Dexedrine or Adderall, you can expect to experience withdrawal symptoms. The timeline and intensity of withdrawal depends on factors like:
- Dosage amount and frequency of use
- Length of time using the medication
- Individual physiology and mental health
Timeline
Withdrawal symptoms from Dexedrine and Adderall typically start within 1 to 2 days of discontinuing the medication. Acute withdrawal symptoms tend to peak within 3 to 5 days. Some symptoms may last 2 to 4 weeks. Post-acute withdrawal syndrome (PAWS) can persist for months.
The most intense symptoms you may experience in the first week include:
- Fatigue and lack of energy: Feeling extremely tired and sluggish. Difficulty getting out of bed.
- Irritability and mood changes: Feelings of restlessness, anger, and agitation. Difficulty controlling emotional reactions.
- Depression: Feeling very sad, hopeless, or worthless. Difficulty experiencing pleasure.
- Anxiety: Feeling worried, nervous, or panicked for no reason. Difficulty relaxing.
- Cravings: Strong urges to take the medication again to relieve withdrawal symptoms.
- Difficulty concentrating: Problems focusing, impaired memory and cognition.
PAWS
Protracted withdrawal symptoms may continue for 6-18 months after stopping stimulants. These include:
- Mild fatigue and lack of motivation
- Mood swings and changes
- Anxiety and problems sleeping
- Difficulty feeling pleasure or reward from activities
The severity of PAWS depends on the dosage and length of time the medications were used. Staying in treatment, practicing self-care, and making lifestyle changes can help manage symptoms during this stage.
The withdrawal process can be difficult, but the symptoms are temporary and will subside over time. Seeking medical detox and rehabilitation treatment increases the chances of successfully overcoming dependence on these stimulants. An addiction specialist can help develop a treatment plan tailored to your needs and ensure a safe recovery.
How to Safely Detox Dexedrine vs Adderall
Detoxing from Dexedrine or Adderall can be challenging, but with medical guidance and support, you can do it safely. The first step is consulting with an addiction specialist to determine the best detox and treatment plan based on your dosage and duration of use.
Tapering
For long-term or high-dose users, abruptly stopping Dexedrine and Adderall can lead to withdrawal symptoms. The safest way to detox is through a gradual dose reduction or tapering. Your doctor will determine a customized tapering schedule to slowly wean you off the medication over weeks or months. This helps minimize withdrawal effects and cravings. Medications and therapy may also be used to manage symptoms during the tapering process.
Medical Detox
Some people may require medically supervised detox, especially if there are co-occurring substance use or mental health disorders. In a detox center, physicians can administer medications to alleviate withdrawal symptoms and provide 24-hour medical monitoring. IV fluids and electrolyte replacement may be needed if dehydration or malnutrition have occurred. The average detox stay is 3 to 7 days.
Withdrawal Management
The most severe symptoms tend to appear within the first week of detox and gradually improve over time. Ongoing treatment and aftercare are critical to maintain sobriety and reduce the risks of relapse. With the right medical and social support, detoxing from Dexedrine and Adderall can be done safely. The rewards of overcoming addiction and reclaiming your health and life are well worth the challenges of the detox process.
Choosing the Right Treatment Center for Stimulant Addiction
Choosing the right treatment center for stimulant addiction like dextroamphetamine (Dexedrine) or mixed amphetamine salts (Adderall) is critical to overcoming dependence and achieving long-term recovery.
Inpatient vs. Outpatient Treatment
Inpatient treatment, also known as residential rehab, provides 24-hour care in a controlled environment. Patients live on-site for the duration of treatment, typically 30 to 90 days. Inpatient rehab is best for those with severe addictions or co-occurring disorders. Outpatient treatment allows patients to live at home while attending day or evening programs several times a week. Outpatient rehab is suitable for those with mild to moderate substance use disorders who require flexibility to maintain work or family responsibilities.
Treatment Methods
Rehab centers utilize various evidence-based treatment methods for stimulant addiction such as behavioral therapies, medication-assisted treatment, holistic therapies, and support groups. Behavioral therapies like cognitive behavioral therapy (CBT) and contingency management teach coping strategies and reward positive behaviors. Medications such as antidepressants may be used to reduce withdrawal symptoms. Holistic therapies like yoga, meditation, and art therapy promote relaxation and self-awareness. Support groups provide a community of those struggling with similar issues.
Aftercare Planning
To maintain sobriety long-term, a comprehensive aftercare plan is essential upon completing a treatment program. This may include ongoing counseling or therapy, medication management, sober living housing, career training, and participation in support groups. Developing new hobbies and social circles that don’t revolve around drug use helps establish a new way of life that is sustainable and fulfilling without the use of stimulants.
The path to overcoming stimulant addiction may feel overwhelming, but with the right treatment and aftercare plan tailored to your needs, sustained recovery is within reach. Do your research to find a reputable rehab center, discuss options with your doctor, and commit to the challenging work of self-improvement—you deserve to live free from dependence.
Help For Dexedrine and Adderall Abuse and Addiction
When it comes to overcoming amphetamine abuse, seeking professional help is vital, and Still Detox Luxury Rehab in Boca Raton, Florida is here to guide you toward lasting recovery. We understand the urgency of addressing amphetamine addiction before it becomes a devastating situation.
Conclusion: Which One Is Right For You?
Choosing between Dexedrine and Adderall for ADHD treatment requires careful consideration of their effectiveness, side effects, and notably, their potential for abuse. Dexedrine’s dextroamphetamine content and Adderall’s combination of amphetamine salts each have distinct therapeutic benefits, but also carry risks of addiction and withdrawal. Understanding these aspects is crucial for informed decision-making, emphasizing the need for vigilant management and awareness of the risks associated with amphetamine and stimulant misuse.
Sources:
Food and Drug Administration. Dexedrine Spansule capsule label
National Institute on Drug Abuse Prescription Stimulants DrugFacts
Lakhan, S.E., & Kirchgessner Prescription stimulants in individuals with and without attention deficit hyperactivity disorder: Misuse, cognitive impact, and adverse effects
